For a chosen cell type and gene, the dotplot shows mean expression and coverage across organ × disease combinations from the PANGEA database.

1. rows = organ  ·  columns = disease
2. dot color = mean expression  &  dot size = coverage (fraction expressing)
3. organ × disease combinations not covered by the database → light grey cell

Enrichment plot

GSEA-style test of preferential expression in Disease (vs Control) and Tumor (vs non-tumor) samples, ranked by gene expression (pseudobulk).

1. NES = normalized ES from 200-permutation null
2. FDR = false discovery rate from the NES permutation null